Sodium a N D Potassium Transport Rates I N Normal H U M a N Leucocytes I N Hypo-osmolal Extracellular

نویسندگان

  • F L U I D
  • J. Patrick
چکیده

1. Sodium and potassium transport rates were studied in normal human leucocytes exposed to iso-osmolal and hypo-osmolal extracellular fluid. 2. Hypo-osmolality of the extracellular fluid led to an increase in sodium influx and a decrease in potassium influx expressed as mmol h-’ kg-’ cell dry weight. The fall in potassium influx was smaller than the rise in sodium influx and was confined to the ouabain-insensitive portion of the flux. 3. The rate constants for sodium and potassium efflux did not differ significantly between the iso-osmolal and hypo-osmolal media.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Amitraz Poisoning; A case study

A m i t r a z, a n i ns e c t i c i d e /a ca ri c i de of the f o r m a m i d i n e p e st i c i d e s group, is a ? 2 a d r e n e r g i c ag on i st a nd of t he a m i d i ne c h e m i ca l f a m il y generally us e d to c o n t r ol animal e c top a r a s i t e s. Poisoning due to am i t r a z i s r a r e and character...

متن کامل

Resolution of Pump and Leak Components of Sodium and Potassium Ion Transport in Human Erythrocytes

Further support for the pump-leak concept was obtained. Net transport was resolved into pump and leak components with the cardiac glycoside, ouabain. The specificity of ouabain as a pump inhibitor was demonstratcd by its ineffectiveness when the pump was already inhibited by lack of one of the three pump substratcs, sodium ion, potassium ion, or adenosine triphosphate. In the presence of ouabai...

متن کامل

On the Associated Primes of the generalized $d$-Local Cohomology Modules

The first part of the paper is concerned to relationship between the sets of associated primes of the generalized $d$-local cohomology modules and the ordinary  generalized local cohomology  modules.  Assume that $R$ is a commutative Noetherian local ring, $M$ and $N$  are  finitely generated  $R$-modules and $d, t$ are two integers. We prove that $Ass H^t_d(M,N)=bigcup_{Iin Phi} Ass H^t_I(M,N)...

متن کامل

The response of the human leucocyte to alterations in extracellular osmolality.

1. The effect of variations in extracellular osmolality from 249 to 345 mosmol/kg upon the sodium, potassium and water content of human leucocytes has been studied. 2. Similar studies were performed using human erythrocytes. 3. Changes in theleucocyte water content were not explicable in terms of passive movement of water across an ‘ideal‘ semi-permeable membrane. 4. Hypo-osmolal swelling was a...

متن کامل

ARTINIANNESS OF COMPOSED LOCAL COHOMOLOGY MODULES

Let $R$ be a commutative Noetherian ring and let $fa$, $fb$ be two ideals of $R$ such that $R/({fa+fb})$ is Artinian. Let $M$, $N$ be two finitely generated $R$-modules. We prove that $H_{fb}^j(H_{fa}^t(M,N))$ is Artinian for $j=0,1$, where $t=inf{iin{mathbb{N}_0}: H_{fa}^i(M,N)$ is not finitelygenerated $}$. Also, we prove that if $DimSupp(H_{fa}^i(M,N))leq 2$, then $H_{fb}^1(H_{fa}^i(M,N))$ i...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2012